Fortunately, I found a really good reference game called "Remember me", there'a scene that happens in the similar scene as we shot:
These are the original 3D elements layer and plate:
For this scene, the feeling I want to catch is dangerous and mysterious, we would defocus the background to let people can't see what's over there exatcly,but still need a lot of details to keep the quality.
The final version completed:
scene. and created the high contrast of the colours.
Red could be the represent of dangerous, so I added the long red light as the main light for it.